Survival-associated eQTLs across different cancer types
We identified 22,212 eQTLs associated with patient overall survival across different cancer types at FDR < 0.05.
|
Cancer type
|
SNP ID
|
SNP position (hg19)
|
Alleles (A/a)
|
log-rank test p-value
|
Sample size
|
Median survival time AA
|
Median survival time Aa
|
Median survival time aa
|
|
|---|---|---|---|---|---|---|---|---|---|
| GBM | rs112642640 | chr17:27007855 | C/T | 2.22E-5 | 146 | 12 | 8.37 | 1.2 | KM Plot |
| GBM | rs112813847 | chr17:27006745 | A/C | 2.07E-5 | 145 | 12 | 7.73 | 1.2 | KM Plot |
| GBM | rs114541894 | chr1:169727473 | G/A | 1.11E-16 | 149 | 11.18 | 11.3 | 0.2 | KM Plot |
| GBM | rs11860837 | chr16:67480263 | A/G | 2.26E-7 | 148 | 12 | 9.55 | 0.97 | KM Plot |
| GBM | rs11918015 | chr3:14695444 | G/T | 7.84E-5 | 148 | 1.1 | 13.13 | 10.87 | KM Plot |
| GBM | rs12166922 | chr22:24311892 | A/G | 1.48E-7 | 142 | 11.9 | 12.73 | 1.62 | KM Plot |
| GBM | rs12345136 | chr9:4317466 | C/T | 6.92E-5 | 149 | 11.9 | 10 | 1.1 | KM Plot |
| GBM | rs12488352 | chr3:14725668 | G/A | 7.4E-5 | 148 | 1.1 | 13.13 | 10.67 | KM Plot |
| GBM | rs12601110 | chr17:27035335 | A/G | 1.77E-5 | 147 | 12.33 | 8.37 | 1.2 | KM Plot |
| GBM | rs12793770 | chr11:1023496 | G/C | 3.34E-8 | 144 | 11.67 | 10.53 | 0.87 | KM Plot |
| GBM | rs1344782 | chr3:14721266 | T/G | 7.11E-5 | 149 | 1.1 | 12.97 | 10.67 | KM Plot |
| GBM | rs1344783 | chr3:14721074 | C/T | 7.11E-5 | 149 | 1.1 | 12.97 | 10.67 | KM Plot |
| GBM | rs139197297 | chr3:14705561 | GA/G | 6.52E-5 | 145 | 10.83 | 14.1 | 1.2 | KM Plot |
| GBM | rs143225517 | chr1:751756 | T/C | 1.89E-5 | 143 | 11.95 | 9.8 | 3.5 | KM Plot |
| GBM | rs144594333 | chr16:67375199 | TCTATAGA/T | 8.62E-8 | 147 | 11.95 | 9.9 | 0.97 | KM Plot |